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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PTPN20A
All Species:
12.73
Human Site:
S57
Identified Species:
40
UniProt:
Q4JDL3
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q4JDL3
NP_001035816.1
420
48423
S57
N
S
E
K
V
K
L
S
L
R
N
F
P
H
N
Chimpanzee
Pan troglodytes
XP_001136909
653
73228
S290
N
S
E
K
V
K
L
S
L
R
N
F
P
H
N
Rhesus Macaque
Macaca mulatta
XP_001109336
420
48468
S57
N
S
E
K
V
K
P
S
L
R
N
F
P
R
N
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O55082
426
49100
S57
N
S
E
N
V
K
P
S
H
H
L
S
F
S
D
Rat
Rattus norvegicus
A1L1L3
421
48562
S57
N
S
E
S
V
K
T
S
H
H
M
S
F
S
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515862
889
97591
G207
K
S
E
K
G
S
L
G
F
T
V
T
K
G
N
Chicken
Gallus gallus
XP_001234615
841
94302
G129
R
S
E
N
N
G
Y
G
F
S
V
V
L
N
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001185050
396
44869
R50
L
Q
N
R
N
D
K
R
E
S
D
E
E
S
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
64
93.5
N.A.
N.A.
64.3
66
N.A.
23.8
25.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
Protein Similarity:
100
64.3
96.6
N.A.
N.A.
77
79.3
N.A.
33.5
37.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
53.3
P-Site Identity:
100
100
86.6
N.A.
N.A.
40
46.6
N.A.
33.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
86.6
N.A.
N.A.
46.6
46.6
N.A.
33.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
13
0
0
0
0
13
0
0
0
13
% D
% Glu:
0
0
88
0
0
0
0
0
13
0
0
13
13
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
25
0
0
38
25
0
0
% F
% Gly:
0
0
0
0
13
13
0
25
0
0
0
0
0
13
0
% G
% His:
0
0
0
0
0
0
0
0
25
25
0
0
0
25
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
13
0
0
50
0
63
13
0
0
0
0
0
13
0
13
% K
% Leu:
13
0
0
0
0
0
38
0
38
0
13
0
13
0
13
% L
% Met:
0
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% M
% Asn:
63
0
13
25
25
0
0
0
0
0
38
0
0
13
63
% N
% Pro:
0
0
0
0
0
0
25
0
0
0
0
0
38
0
0
% P
% Gln:
0
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
13
0
0
13
0
0
0
13
0
38
0
0
0
13
0
% R
% Ser:
0
88
0
13
0
13
0
63
0
25
0
25
0
38
0
% S
% Thr:
0
0
0
0
0
0
13
0
0
13
0
13
0
0
0
% T
% Val:
0
0
0
0
63
0
0
0
0
0
25
13
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
13
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _